Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA036508-07S1
Application #
3174126
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1984-01-01
Project End
1991-12-31
Budget Start
1990-01-01
Budget End
1991-12-31
Support Year
7
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Nguyen, T; Brownell, G L; Holden, S A et al. (1993) Subcellular distribution of various boron compounds and implications for their efficacy in boron neutron capture therapy by Monte Carlo simulations. Radiat Res 133:33-40
Nguyen, T; Brownell, G L; Holden, S A et al. (1993) Intracellular distribution of various boron compounds for use in boron neutron capture therapy. Biochem Pharmacol 45:147-55
Epelbaum, R; Teicher, B A; Holden, S A et al. (1992) Interaction of D,L- and D-tetraplatin with hyperthermia in vitro and in vivo. Eur J Cancer 28A:794-800
Ara, G; Varshney, A; Ha, C S et al. (1992) Multiple modality treatment of carcinoma cells with Pt(Rh-123)2 plus x-ray plus light. Photochem Photobiol 55:561-7
Teicher, B A; Herman, T S; Holden, S A (1991) Effect of pH, oxygenation, and temperature on the cytotoxicity and radiosensitization by etanidazole. Int J Radiat Oncol Biol Phys 20:723-31
Herman, T S; Teicher, B A; Holden, S A (1991) Addition of mitomycin C to cis-diamminedichloroplatinum(II)/hyperthermia/radiation therapy in the FSaIIC fibrosarcoma. Int J Hyperthermia 7:893-903
Teicher, B A; Varshney, A; Khandekar, V et al. (1991) Effect of hypoxia and acidosis on the cytotoxicity of six metal(ligand)4(rhodamine-123)2 complexes at normal and hyperthermic temperatures. Int J Hyperthermia 7:857-68
Teicher, B A; Holden, S A; Herman, T S et al. (1991) Characteristics of five human tumor cell lines and sublines resistant to cis-diamminedichloroplatinum(II). Int J Cancer 47:252-60
Teicher, B A; Pfeffer, M R; Alvarez Sotomayor, E et al. (1991) Schedule dependent tumour growth delay, DNA cross-linking and pharmacokinetic parameters in target tissues with cis-diamminedichloroplatinum(II) and etanidazole with or without hyperthermia or radiation. Int J Hyperthermia 7:773-84
Bubley, G J; Ashburner, B P; Teicher, B A (1991) Spectrum of cis-diamminedichloroplatinum(II)-induced mutations in a shuttle vector propagated in human cells. Mol Carcinog 4:397-406

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