Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA036544-12
Application #
2089129
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1984-07-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Tam, James P; Eom, Khee Dong (2005) Mimicking reverse protein splicing by three-segment tandem peptide ligation. Protein Pept Lett 12:743-9
Eom, Khee Dong; Miao, Zhenwei; Yang, Jin-Long et al. (2003) Tandem ligation of multipartite peptides with cell-permeable activity. J Am Chem Soc 125:73-82
Sadler, Kristen; Eom, Khee Dong; Yang, Jin-Long et al. (2002) Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7. Biochemistry 41:14150-7
Tam, James P; Lu, Yi-An; Yang, Jin-Long (2002) Antimicrobial dendrimeric peptides. Eur J Biochem 269:923-32
Tam, James P; Yu, Qitao (2002) A facile ligation approach to prepare three-helix bundles of HIV fusion-state protein mimetics. Org Lett 4:4167-70
Tam, J P; Yu, Q; Lu, Y A (2001) Tandem peptide ligation for synthetic and natural biologicals. Biologicals 29:189-96
Sun, Y; Lu, G; Tam, J P (2001) A thioester ligation approach to amphipathic bicyclic peptide library. Org Lett 3:1681-4
Tam, J P; Yu, Q; Yang, J L (2001) Tandem ligation of unprotected peptides through thiaprolyl and cysteinyl bonds in water. J Am Chem Soc 123:2487-94
Muhle, S A; Tam, J P (2001) Design of Gram-negative selective antimicrobial peptides. Biochemistry 40:5777-85
Liu, C F; Tam, J P (2001) Subtilisin-catalyzed synthesis of amino acid and peptide esters. Application in a two-step enzymatic ligation strategy. Org Lett 3:4157-9

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