Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA037026-02S1
Application #
3174702
Study Section
(SRC)
Project Start
1985-04-01
Project End
1988-03-31
Budget Start
1986-04-01
Budget End
1987-03-31
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Type
Overall Medical
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Akella, R; Hall, R E (1992) Expression of the adhesion molecules ICAM-1 and ICAM-2 on tumor cell lines does not correlate with their susceptibility to natural killer cell-mediated cytolysis: evidence for additional ligands for effector cell beta integrins. Eur J Immunol 22:1069-74
Noti, J D; Gordon, M; Hall, R E (1992) Human p150,95 alpha-subunit: genomic organization and analysis of the 5'-flanking region. DNA Cell Biol 11:123-38
Kostyal, D A; Beezhold, D H; Hall, R E (1991) Differentiation-inducing cytokine P48 exists in a membrane-associated form. J Immunol 147:893-8
Leftwich, J A; Hall, R E (1990) Initial characterization of a cytokine which induces differentiation and cytolytic activity in HL-60 promyelocytic leukemia cells: evidence that the cytokine is distinct from other known differentiation-active cytokines. J Leukoc Biol 47:87-96
Grant, A J; Merchant, R E; Hall, R E (1989) Interleukin-2 modulates the expression of lymphocyte function-associated antigen-one (LFA-1) and p150,95 during the generation of lymphokine-activated killer (LAK) cells. Immunology 66:117-24
Beezhold, D H; Leftwich, J A; Hall, R E (1989) P48 induces tumor necrosis factor and IL-1 secretion by human monocytes. J Immunol 143:3217-21
Leftwich, J A; Hall, R E (1989) Purification and further characterization of a non-tumor necrosis factor alpha or beta differentiation-inducing cytokine, P48. Cancer Res 49:4459-65
Schuetz, J D; Gorse, K M; Goldman, I D et al. (1988) Transient inhibition of DNA synthesis by 5-fluorodeoxyuridine leads to overexpression of dihydrofolate reductase with increased frequency of methotrexate resistance. J Biol Chem 263:7708-12
Leftwich, J A; Carlson, P; Adelman, B et al. (1987) HL-60-1E3, a novel phorbol diester-resistant HL-60 cell line. Cancer Res 47:1319-24
Ely, C M; Leftwich, J A; Chenevix-Trench, G et al. (1987) Altered regulation of c-myc in an HL-60 differentiation resistant subclone, HL-60-1E3. Cancer Res 47:4595-600

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