Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA037754-07
Application #
3175552
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1985-05-01
Project End
1993-02-28
Budget Start
1991-05-01
Budget End
1992-02-29
Support Year
7
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
Parke Davis Pharmaceutical Research Div
Department
Type
DUNS #
City
Ann Arbor
State
MI
Country
United States
Zip Code
48105

  Publications

Zhu, G; Decker, S J; Mayer, B J et al. (1993) Direct analysis of the binding of the abl Src homology 2 domain to the activated epidermal growth factor receptor. J Biol Chem 268:1775-9
Decker, S J (1993) Transmembrane signaling by epidermal growth factor receptors lacking autophosphorylation sites. J Biol Chem 268:9176-9
Decker, S J; Alexander, C; Habib, T (1992) Epidermal growth factor (EGF)-stimulated tyrosine phosphorylation and EGF receptor degradation in cells expressing EGF receptors truncated at residue 973. J Biol Chem 267:1104-8
Ohmichi, M; Decker, S J; Pang, L et al. (1992) Inhibition of the cellular actions of nerve growth factor by staurosporine and K252A results from the attenuation of the activity of the trk tyrosine kinase. Biochemistry 31:4034-9
Zhu, G; Decker, S J; Saltiel, A R (1992) Direct analysis of the binding of Src-homology 2 domains of phospholipase C to the activated epidermal growth factor receptor. Proc Natl Acad Sci U S A 89:9559-63
Ohmichi, M; Pang, L; Decker, S J et al. (1992) Nerve growth factor stimulates the activities of the raf-1 and the mitogen-activated protein kinases via the trk protooncogene. J Biol Chem 267:14604-10
Ohmichi, M; Decker, S J; Saltiel, A R (1992) Nerve growth factor stimulates the tyrosine phosphorylation of a 38-kDa protein that specifically associates with the src homology domain of phospholipase C-gamma 1. J Biol Chem 267:21601-6
Ohmichi, M; Decker, S J; Saltiel, A R (1992) Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains. Neuron 9:769-77
Brott, B K; Decker, S; Shafer, J et al. (1991) GTPase-activating protein interactions with the viral and cellular Src kinases. Proc Natl Acad Sci U S A 88:755-9
Ohmichi, M; Decker, S J; Pang, L et al. (1991) Nerve growth factor binds to the 140 kd trk proto-oncogene product and stimulates its association with the src homology domain of phospholipase C gamma 1. Biochem Biophys Res Commun 179:217-23

Showing the most recent 10 out of 24 publications