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Ekuase, E J; van 't Erve, T J; Rahaman, A et al. (2016) Mechanistic insights into the specificity of human cytosolic sulfotransferase 2A1 (hSULT2A1) for hydroxylated polychlorinated biphenyls through the use of fluoro-tagged probes. Environ Sci Pollut Res Int 23:2119-27
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Squirewell, Edwin J; Duffel, Michael W (2015) The effects of endoxifen and other major metabolites of tamoxifen on the sulfation of estradiol catalyzed by human cytosolic sulfotransferases hSULT1E1 and hSULT1A1*1. Drug Metab Dispos 43:843-50
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Ekuase, Edugie J; Lehmler, Hans-Joachim; Robertson, Larry W et al. (2014) Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1. Chem Biol Interact 212:56-64
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Squirewell, Edwin J; Qin, Xiaoyan; Duffel, Michael W (2014) Endoxifen and other metabolites of tamoxifen inhibit human hydroxysteroid sulfotransferase 2A1 (hSULT2A1). Drug Metab Dispos 42:1843-50
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Qin, Xiaoyan; Teesch, Lynn M; Duffel, Michael W (2013) Modification of the catalytic function of human hydroxysteroid sulfotransferase hSULT2A1 by formation of disulfide bonds. Drug Metab Dispos 41:1094-103
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Dammanahalli, Jagadeesha K; Duffel, Michael W (2012) Oxidative modification of rat sulfotransferase 1A1 activity in hepatic tissue slices correlates with effects on the purified enzyme. Drug Metab Dispos 40:298-303
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Liu, Yungang; Lehmler, Hans-Joachim; Robertson, Larry W et al. (2011) Physicochemical properties of hydroxylated polychlorinated biphenyls aid in predicting their interactions with rat sulfotransferase 1A1 (rSULT1A1). Chem Biol Interact 189:153-60
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Ekuase, Edugie J; Liu, Yungang; Lehmler, Hans-Joachim et al. (2011) Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1. Chem Res Toxicol 24:1720-8
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Gulcan, Hayrettin Ozan; Duffel, Michael W (2011) Substrate inhibition in human hydroxysteroid sulfotransferase SULT2A1: studies on the formation of catalytically non-productive enzyme complexes. Arch Biochem Biophys 507:232-40
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Liu, Yungang; Smart, Jason T; Song, Yang et al. (2009) Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status. Drug Metab Dispos 37:1065-72
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