Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA039235-09
Application #
2089783
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1992-03-06
Project End
1996-02-29
Budget Start
1994-03-01
Budget End
1996-02-29
Support Year
9
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Roger Williams Hospital
Department
Type
DUNS #
City
Providence
State
RI
Country
United States
Zip Code
02908
Cheng, J C; Frackelton Jr, A R; Bearer, E L et al. (1995) Changes in tyrosine-phosphorylated p190 and its association with p120 type I and p100 type II rasGAPs during myelomonocytic differentiation of human leukemic cells. Cell Growth Differ 6:139-48
Frackelton Jr, A R; Kumar, P S; Kannan, B et al. (1993) Tyrosine phosphorylated proteins in chronic myelogenous leukemia. Leuk Lymphoma 11 Suppl 1:125-9
Buzzi, M; Lu, L; Lombardi Jr, A J et al. (1992) Differentiation-induced changes in protein-tyrosine phosphatase activity and commensurate expression of CD45 in human leukemia cell lines. Cancer Res 52:4027-35
Beitz, J G; Kim, I S; Calabresi, P et al. (1991) Human microvascular endothelial cells express receptors for platelet-derived growth factor. Proc Natl Acad Sci U S A 88:2021-5
Frackelton Jr, A R; Posner, M; Kannan, B et al. (1991) Generation of monoclonal antibodies against phosphotyrosine and their use for affinity purification of phosphotyrosine-containing proteins. Methods Enzymol 201:79-92
Huhn, R D; Cicione, M E; Frackelton Jr, A R (1989) Identification of tyrosine-phosphorylated colony-stimulating factor 1 (CSF-1) receptor and a 56-kilodalton protein phosphorylated in intact human cells in response to CSF-1. J Cell Biochem 39:129-37
Sengupta, A; Liu, W K; Yeung, Y G et al. (1988) Identification and subcellular localization of proteins that are rapidly phosphorylated in tyrosine in response to colony-stimulating factor 1. Proc Natl Acad Sci U S A 85:8062-6
Huhn, R D; Posner, M R; Rayter, S I et al. (1987) Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residues. Proc Natl Acad Sci U S A 84:4408-12
Bell, J C; Mahadevan, L C; Colledge, W H et al. (1987) Abelson-transformed fibroblasts contain nuclear phosphotyrosyl-proteins which preferentially bind to murine DNA. Nature 325:552-4
Daniel, T O; Tremble, P M; Frackelton Jr, A R et al. (1985) Purification of the platelet-derived growth factor receptor by using an anti-phosphotyrosine antibody. Proc Natl Acad Sci U S A 82:2684-7