Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA040162-04
Application #
3179743
Study Section
Pathology B Study Section (PTHB)
Project Start
1986-04-01
Project End
1989-08-31
Budget Start
1989-04-01
Budget End
1989-08-31
Support Year
4
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Arizona
Department
Type
Schools of Medicine
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85722
Kolb, Armin; Kleeff, Jorg; Arnold, Nichole et al. (2007) Expression and differential signaling of heregulins in pancreatic cancer cells. Int J Cancer 120:514-23
Liu, Zhanbing; Neiss, Nicola; Zhou, Shaoxia et al. (2007) Identification of a fibroblast growth factor receptor 1 splice variant that inhibits pancreatic cancer cell growth. Cancer Res 67:2712-9
Kayed, Hany; Kleeff, Jorg; Kolb, Armin et al. (2006) FXYD3 is overexpressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth. Int J Cancer 118:43-54
Chan, John K; Pham, Huyen; You, Xue Juan et al. (2005) Suppression of ovarian cancer cell tumorigenicity and evasion of Cisplatin resistance using a truncated epidermal growth factor receptor in a rat model. Cancer Res 65:3243-8
Kleeff, Jorg; Kothari, Nayantara H; Friess, Helmut et al. (2004) Adenovirus-mediated transfer of a truncated fibroblast growth factor (FGF) type I receptor blocks FGF-2 signaling in multiple pancreatic cancer cell lines. Pancreas 28:25-30
Guo, Junchao; Kleeff, Jorg; Li, Junsheng et al. (2004) Expression and functional significance of CDC25B in human pancreatic ductal adenocarcinoma. Oncogene 23:71-81
Liao, Quan; Guo, Junchao; Kleeff, Jorg et al. (2003) Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells. Gastroenterology 124:1830-45
Friess, H; Ding, J; Kleeff, J et al. (2003) Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer. Cell Mol Life Sci 60:1180-99
Ketterer, Knut; Rao, Shyam; Friess, Helmut et al. (2003) Reverse transcription-PCR analysis of laser-captured cells points to potential paracrine and autocrine actions of neurotrophins in pancreatic cancer. Clin Cancer Res 9:5127-36
Matsuda, Kei; Idezawa, Takenao; You, Xue Juan et al. (2002) Multiple mitogenic pathways in pancreatic cancer cells are blocked by a truncated epidermal growth factor receptor. Cancer Res 62:5611-7

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