Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA040575-09
Application #
3180737
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1985-09-05
Project End
1994-06-30
Budget Start
1993-03-25
Budget End
1993-06-30
Support Year
9
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Aastrom Biosciences, Inc.
Department
Type
DUNS #
City
Ann Arbor
State
MI
Country
United States
Zip Code
48105
Phillips, R L; Couzens, M S; Van Zant, G (1995) Genetic factors influencing murine hematopoietic productivity in culture. J Cell Physiol 164:99-107
Yu, H; Bauer, B; Lipke, G K et al. (1993) Apoptosis and hematopoiesis in murine fetal liver. Blood 81:373-84
Phillips, R L; Reinhart, A J; Van Zant, G (1992) Genetic control of murine hematopoietic stem cell pool sizes and cycling kinetics. Proc Natl Acad Sci U S A 89:11607-11
Van Zant, G; Scott-Micus, K; Thompson, B P et al. (1992) Stem cell quiescence/activation is reversible by serial transplantation and is independent of stromal cell genotype in mouse aggregation chimeras. Exp Hematol 20:470-5
Van Zant, G; Thompson, B P; Chen, J J (1991) Differentiation of chimeric bone marrow in vivo reveals genotype-restricted contributions to hematopoiesis. Exp Hematol 19:941-9
Van Zant, G; Chen, J J; Scott-Micus, K (1991) Developmental potential of hematopoietic stem cells determined using retrovirally marked allophenic marrow. Blood 77:756-63
Van Zant, G; Holland, B P; Eldridge, P W et al. (1990) Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice. J Exp Med 171:1547-65
Buller, R S; Van Zant, G; Eldridge, P W et al. (1989) A population of murine hematopoietic progenitors expresses an endogenous retroviral gp70 linked to the Rmcf gene and associated with resistance to erythroleukemia. J Exp Med 169:865-80
Van Zant, G; Shultz, L (1989) Hematologic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev). Exp Hematol 17:81-7
Worthington, R E; Bossie-Codreanu, J; Van Zant, G (1987) Quantitation of erythroid differentiation in vitro using a sensitive colorimetric assay for hemoglobin. Exp Hematol 15:85-92