Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA042276-08S1
Application #
2090651
Study Section
Experimental Immunology Study Section (EI)
Project Start
1986-09-01
Project End
1995-06-30
Budget Start
1993-07-01
Budget End
1995-06-30
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Henderson, Barbara W; Gollnick, Sandra O; Snyder, John W et al. (2004) Choice of oxygen-conserving treatment regimen determines the inflammatory response and outcome of photodynamic therapy of tumors. Cancer Res 64:2120-6
Shaw, L M; Mercurio, A M (1995) Regulation of alpha 6 beta 1 integrin-mediated migration in macrophages. Agents Actions Suppl 47:101-6
Shaw, L M; Turner, C E; Mercurio, A M (1995) The alpha 6A beta 1 and alpha 6B beta 1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins. J Biol Chem 270:23648-52
Shaw, L M; Mercurio, A M (1994) Regulation of cellular interactions with laminin by integrin cytoplasmic domains: the A and B structural variants of the alpha 6 beta 1 integrin differentially modulate the adhesive strength, morphology, and migration of macrophages. Mol Biol Cell 5:679-90
Lotz, M M; Andrews Jr, C W; Korzelius, C A et al. (1993) Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma. Proc Natl Acad Sci U S A 90:3466-70
Shaw, L M; Lotz, M M; Mercurio, A M (1993) Inside-out integrin signaling in macrophages. Analysis of the role of the alpha 6A beta 1 and alpha 6B beta 1 integrin variants in laminin adhesion by cDNA expression in an alpha 6 integrin-deficient macrophage cell line. J Biol Chem 268:11401-8
Messier, J M; Shaw, L M; Chafel, M et al. (1993) Fimbrin localized to an insoluble cytoskeletal fraction is constitutively phosphorylated on its headpiece domain in adherent macrophages. Cell Motil Cytoskeleton 25:223-33
Shaw, L M; Mercurio, A M (1993) Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit. J Cell Biol 123:1017-25
Lee, E C; Lotz, M M; Steele Jr, G D et al. (1992) The integrin alpha 6 beta 4 is a laminin receptor. J Cell Biol 117:671-8
Woo, H J; Lotz, M M; Jung, J U et al. (1991) Carbohydrate-binding protein 35 (Mac-2), a laminin-binding lectin, forms functional dimers using cysteine 186. J Biol Chem 266:18419-22

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