Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA044794-02
Application #
3187584
Study Section
Experimental Immunology Study Section (EI)
Project Start
1987-05-01
Project End
1992-04-30
Budget Start
1988-05-01
Budget End
1989-04-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Morganelli, P M; Kitzmiller, T J; Hemmer, R et al. (1992) Redirected targeting of LDL to human monocyte Fc gamma receptors with bispecific antibodies. Arterioscler Thromb 12:1131-8
Shen, L (1992) A monoclonal antibody specific for immunoglobulin A receptor triggers polymorphonuclear neutrophil superoxide release. J Leukoc Biol 51:373-8
Connor, R I; Dinces, N B; Howell, A L et al. (1991) Fc receptors for IgG (Fc gamma Rs) on human monocytes and macrophages are not infectivity receptors for human immunodeficiency virus type 1 (HIV-1): studies using bispecific antibodies to target HIV-1 to various myeloid cell surface molecules, including t Proc Natl Acad Sci U S A 88:9593-7
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Pfefferkorn, L C; Guyre, P M; Fanger, M W (1990) Functional comparison of the inductions of NADPH oxidase activity and Fc gamma RI in IFN gamma-treated U937 cells. Mol Immunol 27:263-72
Shen, L; Collins, J (1989) Monocyte superoxide secretion triggered by human IgA. Immunology 68:491-6
Pfefferkorn, L C; Fanger, M W (1989) Transient activation of the NADPH oxidase through Fc gamma RI. Oxidase deactivation precedes internalization of cross-linked receptors. J Immunol 143:2640-9
Graziano, R F; Erbe, D V; Fanger, M W (1989) The mechanisms of antibody-dependent killing mediated by lymphoid and myeloid cells are distinct based on different divalent cation requirements. J Immunol 143:3894-900

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