Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA045484-06S1
Application #
2091893
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1989-07-01
Project End
1995-07-31
Budget Start
1994-08-01
Budget End
1995-07-31
Support Year
6
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Matory, Y L; Dorfman, D M; Chen, M et al. (1999) T cells mediate treatment of six-day-old cytokine-gene-transfected mouse mammary tumor. Pathobiology 67:3-11
Linehan, D C; Goedegebuure, P S; Eberlein, T J (1996) Vaccine therapy for cancer. Ann Surg Oncol 3:219-28
Matory, Y L; Chen, M; Dorfman, D M et al. (1995) Antitumor activity of three mouse mammary cancer cell lines after interferon-gamma gene transfection. Surgery 118:251-5;discussion 255-6
Peoples, G E; Goedegebuure, P S; Smith, R et al. (1995) Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide. Proc Natl Acad Sci U S A 92:432-6
Burger, U L; Chang, M P; Goedegebuure, P S et al. (1995) Recruitment of host CD8+ T cells by tumor-infiltrating lymphocytes and recombinant interleukin-2 during adoptive immunotherapy of cancer. Surgery 117:325-33
Peoples, G E; Blotnick, S; Takahashi, K et al. (1995) T lymphocytes that infiltrate tumors and atherosclerotic plaques produce heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor: a potential pathologic role. Proc Natl Acad Sci U S A 92:6547-51
Matory, Y L; Chen, M; Goedegebuure, P S et al. (1995) Anti-tumor effects and tumor immunogenicity following IL2 or IL4 cytokine gene transfection of three mouse mammary tumors. Ann Surg Oncol 2:502-11
Linehan, D C; Goedegebuure, P S; Peoples, G E et al. (1995) Tumor-specific and HLA-A2-restricted cytolysis by tumor-associated lymphocytes in human metastatic breast cancer. J Immunol 155:4486-91
Lee, K Y; Goedegebuure, P S; Linehan, D C et al. (1995) Immunoregulatory effects of CD4+ T helper subsets in human melanoma. Surgery 117:365-72
Peoples, G E; Smith, R C; Linehan, D C et al. (1995) Shared T cell epitopes in epithelial tumors. Cell Immunol 164:279-86

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