Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA045642-10
Application #
2091954
Study Section
Molecular Biology Study Section (MBY)
Project Start
1987-09-17
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ariad Pharmaceuticals, Inc.
Department
Type
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Vignais, M L; Gilman, M (1999) Distinct mechanisms of activation of Stat1 and Stat3 by platelet-derived growth factor receptor in a cell-free system. Mol Cell Biol 19:3727-35
Harrison, D A; McCoon, P E; Binari, R et al. (1998) Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway. Genes Dev 12:3252-63
Grueneberg, D A; Henry, R W; Brauer, A et al. (1997) A multifunctional DNA-binding protein that promotes the formation of serum response factor/homeodomain complexes: identity to TFII-I. Genes Dev 11:2482-93
Simon, K J; Grueneberg, D A; Gilman, M (1997) Protein and DNA contact surfaces that mediate the selective action of the Phox1 homeodomain at the c-fos serum response element. Mol Cell Biol 17:6653-62
Vignais, M L; Sadowski, H B; Watling, D et al. (1996) Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. Mol Cell Biol 16:1759-69
Grueneberg, D A; Simon, K J; Brennan, K et al. (1995) Sequence-specific targeting of nuclear signal transduction pathways by homeodomain proteins. Mol Cell Biol 15:3318-26
Harrison, D A; Binari, R; Nahreini, T S et al. (1995) Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J 14:2857-65
Natesan, S; Gilman, M (1995) YY1 facilitates the association of serum response factor with the c-fos serum response element. Mol Cell Biol 15:5975-82
Lee, G; Gilman, M (1994) Dual modes of control of c-fos mRNA induction by intracellular calcium in T cells. Mol Cell Biol 14:4579-87
Sadowski, H B; Shuai, K; Darnell Jr, J E et al. (1993) A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science 261:1739-44

Showing the most recent 10 out of 21 publications