Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA045735-08
Application #
2091989
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1991-09-30
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Martin, B D; Schoenhard, J A; Sugden, K D (1998) Hypervalent chromium mimics reactive oxygen species as measured by the oxidant-sensitive dyes 2',7'-dichlorofluorescin and dihydrorhodamine. Chem Res Toxicol 11:1402-10
Shumilla, J A; Wetterhahn, K E; Barchowsky, A (1998) Inhibition of NF-kappa B binding to DNA by chromium, cadmium, mercury, zinc, and arsenite in vitro: evidence of a thiol mechanism. Arch Biochem Biophys 349:356-62
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Borges, K M; Boswell, J S; Liebross, R H et al. (1991) Activation of chromium(VI) by thiols results in chromium(V) formation, chromium binding to DNA and altered DNA conformation. Carcinogenesis 12:551-61
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