Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA045768-09A1
Application #
2007665
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1988-07-01
Project End
1997-06-30
Budget Start
1996-09-27
Budget End
1997-06-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118
Istfan, N W; Person, K S; Holick, M F et al. (2007) 1alpha,25-Dihydroxyvitamin D and fish oil synergistically inhibit G1/S-phase transition in prostate cancer cells. J Steroid Biochem Mol Biol 103:726-30
Istfan, Nawfal W; Chen, Zhi-Yi; Rex, Sybille (2002) Fish oil slows S phase progression and may cause upstream shift of DHFR replication origin ori-beta in CHO cells. Am J Physiol Cell Physiol 283:C1009-24
Rex, Sybille; Kukuruzinska, Maria A; Istfan, Nawfal W (2002) Inhibition of DNA replication by fish oil-treated cytoplasm is counteracted by fish oil-treated nuclear extract. Am J Physiol Cell Physiol 283:C1365-75
Chen, Z Y; Istfan, N W (2001) Docosahexaenoic acid, a major constituent of fish oil diets, prevents activation of cyclin-dependent kinases and S-phase entry by serum stimulation in HT-29 cells. Prostaglandins Leukot Essent Fatty Acids 64:67-73
Chen, Z Y; Istfan, N W (2000) Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells. Prostaglandins Leukot Essent Fatty Acids 63:301-8
Istfan, N W; Wan, J M; Bistrian, B R et al. (1994) DNA replication time accounts for tumor growth variation induced by dietary fat in a breast carcinoma model. Cancer Lett 86:177-86
Wan, J M; Bistrian, B R; Figoni, M A et al. (1994) Influence of interleukin-2 infusion on cell cycle kinetics in the Walker-256 carcinosarcoma. J Leukoc Biol 55:241-7
Ling, P R; Bistrian, B R; Mendez, B et al. (1994) Effects of systemic infusions of endotoxin, tumor necrosis factor, and interleukin-1 on glucose metabolism in the rat: relationship to endogenous glucose production and peripheral tissue glucose uptake. Metabolism 43:279-84
Wan, J M; Fogt, F; Bistrian, B R et al. (1993) Evaluation of antitumor effect of tumor necrosis factor in terms of protein metabolism and cell cycle kinetics. Am J Physiol 265:C365-74
Ye, S L; Istfan, N W; Driscoll, D F et al. (1992) Tumor and host response to arginine and branched chain amino acid-enriched total parenteral nutrition. A study involving Walker 256 carcinosarcoma-bearing rats. Cancer 69:261-70

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