Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA046776-06
Application #
2092295
Study Section
Radiation Study Section (RAD)
Project Start
1988-03-01
Project End
1997-09-29
Budget Start
1995-09-30
Budget End
1997-09-29
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Palayoor, S T; Bump, E A; Teicher, B A et al. (1997) Apoptosis and clonogenic cell death in PC3 human prostate cancer cells after treatment with gamma radiation and suramin. Radiat Res 148:105-14
Braunhut, S J; Medeiros, D; Lai, L et al. (1996) Tempol prevents impairment of the endothelial cell wound healing response caused by ionising radiation. Br J Cancer Suppl 27:S157-60
Palayoor, S T; Macklis, R M; Bump, E A et al. (1995) Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells. Radiat Res 141:235-43
Langley, R E; Quartuccio, S G; Kennealey, P T et al. (1995) Effect of cell cycle stage, dose rate and repair of sublethal damage on radiation-induced apoptosis in F9 teratocarcinoma cells. Radiat Res 144:90-6
Braunhut, S J; Moses, M A (1994) Retinoids modulate endothelial cell production of matrix-degrading proteases and tissue inhibitors of metalloproteinases (TIMP). J Biol Chem 269:13472-9
Langley, R E; Palayoor, S T; Coleman, C N et al. (1994) Radiation-induced apoptosis in F9 teratocarcinoma cells. Int J Radiat Biol 65:605-10
Bump, E A; Braunhut, S J; Palayoor, S T et al. (1994) Novel concepts in modification of radiation sensitivity. Int J Radiat Oncol Biol Phys 29:249-53
Bump, E A; al-Sarraf, R; Pierce, S M et al. (1992) Elevation of mouse kidney thiol content following administration of glutathione. Radiother Oncol 23:21-5
Bump, E A; Cerce, B A; al-Sarraf, R et al. (1992) Radioprotection of DNA in isolated nuclei by naturally occurring thiols at intermediate oxygen tension. Radiat Res 132:94-104