Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA046843-10S1
Application #
2646807
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1988-03-01
Project End
2001-01-31
Budget Start
1997-02-01
Budget End
1998-01-31
Support Year
10
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
McCawley, Lisa J; Crawford, Howard C; King Jr, Lloyd E et al. (2004) A protective role for matrix metalloproteinase-3 in squamous cell carcinoma. Cancer Res 64:6965-72
Leite-Browning, Maria L; McCawley, Lisa J; Jahnen-Dechent, Willi et al. (2004) Alpha 2-HS glycoprotein (fetuin-A) modulates murine skin tumorigenesis. Int J Oncol 25:319-24
Leite-Browning, Maria L; McCawley, Lisa J; Choi, Oksoon H et al. (2002) Interactions of alpha2-HS-glycoprotein (fetuin) with MMP-3 and murine squamous cell carcinoma cells. Int J Oncol 21:965-71
Hulboy, D L; Matrisian, L M; Crawford, H C (2001) Loss of JunB activity enhances stromelysin 1 expression in a model of the epithelial-to-mesenchymal transition of mouse skin tumors. Mol Cell Biol 21:5478-87
Haro, H; Crawford, H C; Fingleton, B et al. (2000) Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption. J Clin Invest 105:143-50
Haro, H; Crawford, H C; Fingleton, B et al. (2000) Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption. J Clin Invest 105:133-41
Nelson, A R; Fingleton, B; Rothenberg, M L et al. (2000) Matrix metalloproteinases: biologic activity and clinical implications. J Clin Oncol 18:1135-49
Rudolph-Owen, L A; Matrisian, L M (1998) Matrix metalloproteinases in remodeling of the normal and neoplastic mammary gland. J Mammary Gland Biol Neoplasia 3:177-89
Crawford, H C; Matrisian, L M; Liaw, L (1998) Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo. Cancer Res 58:5206-15
Hulboy, D L; Rudolph, L A; Matrisian, L M (1997) Matrix metalloproteinases as mediators of reproductive function. Mol Hum Reprod 3:27-45

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