Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA046896-01A2
Application #
3190383
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1989-04-01
Project End
1992-03-31
Budget Start
1989-04-01
Budget End
1990-03-31
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Sharma, M; Jain, R (1998) Isolation and analysis of dityrosine from enzyme-catalyzed oxidation of tyrosine and X-irradiated peptide and proteins. Chem Biol Interact 108:171-85
Jain, R; Freund, H G; Budzinsky, E et al. (1997) Radiation-induced formation of 3,4-dihydroxyphenylalanine in tyrosine-containing peptides and proteins as a function of X-irradiation dose. Bioconjug Chem 8:173-8
Sharma, M; Jain, R; Ionescu, E et al. (1995) Quantitative analysis of 3'-azido-3'-deoxythymidine incorporation into DNA in human colon tumor cells. Bioconjug Chem 6:536-40
Sharma, M; Jain, R; Ionescu, E et al. (1995) Capillary electrophoretic separation and laser-induced fluorescence detection of the major DNA adducts of cisplatin and carboplatin. Anal Biochem 228:307-11
Azadnia, A; Campbell, R; Sharma, M (1994) The scope of dansyl vs fluorescein label in fluorescence postlabeling assay for DNA damage. Anal Biochem 218:444-8
Jain, R; Isac, T V; Sharma, M (1994) Fluorescence postlabeling assay of RNA modification. Biochem Biophys Res Commun 200:1239-44
Jain, R; Sharma, M (1993) Fluorescence postlabeling assay of DNA damage induced by N-methyl-N-nitrosourea. Cancer Res 53:2771-4
Lee, T; Yeung, E S; Sharma, M (1991) Micellar electrokinetic capillary chromatographic separation and laser-induced fluorescence detection of 2'-deoxynucleoside 5'-monophosphates of normal and modified bases. J Chromatogr 565:197-206
Sharma, M; Jain, R (1991) Nuclease P1-mediated fluorescence postlabeling assay of AAF modified DNA model d(TACGTA) and calf-thymus DNA. Biochem Biophys Res Commun 177:151-8
Sharma, M; Jain, R; Isac, T V (1991) A novel technique to assay adducts of DNA induced by anticancer agent cis-diamminedichloroplatinum(II). Bioconjug Chem 2:403-6

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