Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA047307-01
Application #
3190865
Study Section
Experimental Immunology Study Section (EI)
Project Start
1988-05-01
Project End
1991-04-30
Budget Start
1988-05-01
Budget End
1989-04-30
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Rockefeller University
Department
Type
Graduate Schools
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
Liu, C C; Young, J D (2001) Uterine natural killer cells in the pregnant uterus. Adv Immunol 79:297-329
Liu, C C; Perussia, B; Young, J D (2000) The emerging role of IL-15 in NK-cell development. Immunol Today 21:113-6
Matloubian, M; Suresh, M; Glass, A et al. (1999) A role for perforin in downregulating T-cell responses during chronic viral infection. J Virol 73:2527-36
Laochumroonvorapong, P; Wang, J; Liu, C C et al. (1997) Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice. Infect Immun 65:127-32
Liu, C C; Young, L H; Young, J D (1996) Lymphocyte-mediated cytolysis and disease. N Engl J Med 335:1651-9
Horta, M F; Fu, K C; Koizumi, H et al. (1996) Cell-free conversion of a ubiquitous nuclear protein into a killer-cell-specific form that binds to the NF-P enhancer element of the mouse perforin gene. Eur J Biochem 238:639-46
Liu, C C; Persechini, P M; Young, J D (1996) Expression and characterization of functionally active recombinant perforin produced in insect cells. J Immunol 156:3292-300
Ye, W; Zheng, L M; Young, J D et al. (1996) The involvement of interleukin (IL)-15 in regulating the differentiation of granulated metrial gland cells in mouse pregnant uterus. J Exp Med 184:2405-10
Ye, W; Young, J D; Liu, C C (1996) Interleukin-15 induces the expression of mRNAs of cytolytic mediators and augments cytotoxic activities in primary murine lymphocytes. Cell Immunol 174:54-62
Liu, C C; Walsh, C M; Eto, N et al. (1995) Morphologic and functional characterization of perforin-deficient lymphokine-activated killer cells. J Immunol 155:602-8

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