Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA047333-03
Application #
3190902
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1988-04-01
Project End
1991-03-31
Budget Start
1990-04-01
Budget End
1991-03-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Type
Schools of Arts and Sciences
DUNS #
City
University Park
State
PA
Country
United States
Zip Code
16802
Chackalaparampil, I; Bagrodia, S; Shalloway, D (1994) Tyrosine dephosphorylation of pp60c-src is stimulated by a serine/threonine phosphatase inhibitor. Oncogene 9:1947-55
Hotz-Wagenblatt, A; Shalloway, D (1993) Gap junctional communication and neoplastic transformation. Crit Rev Oncog 4:541-58
David-Pfeuty, T; Bagrodia, S; Shalloway, D (1993) Differential localization patterns of myristoylated and nonmyristoylated c-Src proteins in interphase and mitotic c-Src overexpresser cells. J Cell Sci 105 ( Pt 3):613-28
Bagrodia, S; Taylor, S J; Shalloway, D (1993) Myristylation is required for Tyr-527 dephosphorylation and activation of pp60c-src in mitosis. Mol Cell Biol 13:1464-70
Shalloway, D; Bagrodia, S; Chackalaparampil, I et al. (1992) c-Src and mitosis. Ciba Found Symp 170:248-65;discussion 265-75
Shenoy, S; Chackalaparampil, I; Bagrodia, S et al. (1992) Role of p34cdc2-mediated phosphorylations in two-step activation of pp60c-src during mitosis. Proc Natl Acad Sci U S A 89:7237-41
Roussel, R R; Brodeur, S R; Shalloway, D et al. (1991) Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src. Proc Natl Acad Sci U S A 88:10696-700
Shalloway, D; Shenoy, S (1991) Oncoprotein kinases in mitosis. Adv Cancer Res 57:185-225
Mehta, P P; Hotz-Wagenblatt, A; Rose, B et al. (1991) Incorporation of the gene for a cell-cell channel protein into transformed cells leads to normalization of growth. J Membr Biol 124:207-25
Ames, R S; Holskin, B; Mitcho, M et al. (1990) Induction of sensitivity to the cytotoxic action of tumor necrosis factor alpha by adenovirus E1A is independent of transformation and transcriptional activation. J Virol 64:4115-22

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