Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA047404-03S1
Application #
3191042
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1988-04-05
Project End
1992-03-31
Budget Start
1990-04-01
Budget End
1992-03-31
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Asea, Alexzander; Rehli, Michael; Kabingu, Edith et al. (2002) Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem 277:15028-34
Rodland, K D; Lenormand, P; Muldoon, L L et al. (1992) Regulation of transin/stromelysin and VL30 gene expression by intracellular calcium. J Invest Dermatol 98:12S-16S
Pribnow, D; Muldoon, L L; Fajardo, M et al. (1992) Endothelin induces transcription of fos/jun family genes: a prominent role for calcium ion. Mol Endocrinol 6:1003-12
Foley, J F; Moertel, C G (1991) Improving accrual into cancer clinical trials. J Cancer Educ 6:165-73
Rodland, K D; Muldoon, L L; Magun, B E (1991) Regulation of intracellular Ca2+ and gene expression by endothelin-1. J Cardiovasc Pharmacol 17 Suppl 7:S89-95
Muldoon, L L; Enslen, H; Rodland, K D et al. (1991) Stimulation of Ca2+ influx by endothelin-1 is subject to negative feedback by elevated intracellular Ca2+. Am J Physiol 260:C1273-81
Rodland, K D; Muldoon, L L; Magun, B E (1990) Cellular mechanisms of TGF-beta action. J Invest Dermatol 94:33S-40S
Lenormand, P; Muldoon, L L; Enslen, H et al. (1990) Two tumor promoters, 12-O-tetradecanoylphorbol-13-acetate and thapsigargin, act synergistically via distinct signaling pathways to stimulate gene expression. Cell Growth Differ 1:627-35
Rodland, K D; Muldoon, L L; Lenormand, P et al. (1990) Modulation of RNA expression by intracellular calcium. Existence of a threshold calcium concentration for induction of VL30 RNA by epidermal growth factor, endothelin, and protein kinase C. J Biol Chem 265:11000-7
Muldoon, L L; Pribnow, D; Rodland, K D et al. (1990) Endothelin-1 stimulates DNA synthesis and anchorage-independent growth of Rat-1 fibroblasts through a protein kinase C-dependent mechanism. Cell Regul 1:379-90

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