Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA047411-08
Application #
2092547
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1988-06-01
Project End
1997-05-31
Budget Start
1995-06-01
Budget End
1997-05-31
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Charles, Michael A; Saunders, Thomas L; Wood, William M et al. (2006) Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function. Mol Endocrinol 20:1366-77
Christoffolete, Marcelo A; Ribeiro, Rogerio; Singru, Praful et al. (2006) Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism. Endocrinology 147:1735-43
Gordon, David F; Tucker, Elizabeth A; Tundwal, Kavita et al. (2006) MED220/thyroid receptor-associated protein 220 functions as a transcriptional coactivator with Pit-1 and GATA-2 on the thyrotropin-beta promoter in thyrotropes. Mol Endocrinol 20:1073-89
Sarapura, Virginia D; Wood, William M; Woodmansee, Whitney W et al. (2006) Pituitary tumors arising from glycoprotein hormone alpha-subunit-deficient mice contain transcription factors and receptors present in thyrotropes. Pituitary 9:11-8
Woodmansee, Whitney W; Kerr, Janice M; Tucker, Elizabeth A et al. (2006) The proliferative status of thyrotropes is dependent on modulation of specific cell cycle regulators by thyroid hormone. Endocrinology 147:272-82
Kerr, Janice M; Gordon, David F; Woodmansee, Whitney W et al. (2005) Growth arrest of thyrotropic tumors by thyroid hormone is correlated with novel changes in Wnt-10A. Mol Cell Endocrinol 238:57-67
Woodmansee, Whitney W; Mouser, Rhonda L; Gordon, David F et al. (2002) Mutational analysis of the mouse somatostatin receptor type 5 gene promoter. Endocrinology 143:2268-76
Wood, William M; Sarapura, Virginia D; Dowding, Janet M et al. (2002) Early gene expression changes preceding thyroid hormone-induced involution of a thyrotrope tumor. Endocrinology 143:347-59
Brinkmeier, M L; Stahl, J H; Gordon, D F et al. (2001) Thyroid hormone-responsive pituitary hyperplasia independent of somatostatin receptor 2. Mol Endocrinol 15:2129-36
Woodmansee, W W; Gordon, D F; Dowding, J M et al. (2000) The effect of thyroid hormone and a long-acting somatostatin analogue on TtT-97 murine thyrotropic tumors. Thyroid 10:533-41

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