Study of Novel Cytokine Derived From Hodgkin's Cell Line

Hsu, Su-Ming

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 7R01CA047462-04
• Application #: 3191119
• Study Section: Pathology B Study Section (PTHB)
• Project Start: 1988-04-01
• Project End: 1992-11-30
• Budget Start: 1991-05-17
• Budget End: 1992-11-30
• Support Year: 4
• Fiscal Year: 1990

Institution

• Name: University of Arkansas for Medical Sciences
• Type: Schools of Medicine
• City: Little Rock
• State: AR
• Country: United States
• Zip Code: 72205

Publications

Hsu, S M; Lin, J; Xie, S S et al. (1993) Abundant expression of transforming growth factor-beta 1 and -beta 2 by Hodgkin's Reed-Sternberg cells and by reactive T lymphocytes in Hodgkin's disease. Hum Pathol 24:249-55

el-Okda, M; Hyeh, Y; Xie, S S et al. (1992) Russell bodies consist of heterogenous glycoproteins in B-cell lymphoma cells. Am J Clin Pathol 97:866-71

Collins, C L; Ordonez, N G; Schaefer, R et al. (1992) Thrombomodulin expression in malignant pleural mesothelioma and pulmonary adenocarcinoma. Am J Pathol 141:827-33

Hsu, P L; Lin, Y C; Hsu, S M (1991) Expression of macrophage colony-stimulating factor (M-CSF) in two Hodgkin's Reed-Sternberg (H-RS) cell lines, HDLM-1 and KM-H2, and in H-RS cells in tissues. Int J Hematol 54:315-26

Hsu, S M; Xie, S S; Hsu, P L (1990) Cultured Reed-Sternberg cells HDLM-1 and KM-H2 can be induced to become histiocytelike cells. H-RS cells are not derived from lymphocytes. Am J Pathol 137:353-67

Hsu, S M; Hsu, P L (1990) Lack of effect of colony-stimulating factors, interleukins, interferons, and tumor necrosis factor on the growth and differentiation of cultured Reed-Sternberg cells. Comparison with effects of phorbol ester and retinoic acid. Am J Pathol 136:181-9

Hsu, S M; Hsu, P L (1990) Lymphocyte functional antigens stabilize agglutination between Reed-Sternberg cells and T cells, but are not responsible for homotypic binding of Hodgkin's Reed-Sternberg cells. Am J Pathol 137:563-74

Hsu, S M; Tseng, C K; Hsu, P L (1990) Expression of p55 (Tac) interleukin-2 receptor (IL-2R), but not p75 IL-2R, in cultured H-RS cells and H-RS cells in tissues. Am J Pathol 136:735-44

Hsu, P L; Hsu, S M (1989) Production of tumor necrosis factor-alpha and lymphotoxin by cells of Hodgkin's neoplastic cell lines HDLM-1 and KM-H2. Am J Pathol 135:735-45

Hsu, S M; Krupen, K; Lachman, L B (1989) Heterogeneity of interleukin 1 production in cultured Reed-Sternberg cell lines HDLM-1, HDLM-1d, and KM-H2. Am J Pathol 135:33-8