Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA050175-03
Application #
3194492
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1989-08-01
Project End
1992-08-31
Budget Start
1991-06-17
Budget End
1991-08-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Basu, A; Kozikowski, A P; Lazo, J S (1992) Structural requirements of lyngbyatoxin A for activation and downregulation of protein kinase C. Biochemistry 31:3824-30
Kozikowski, A P; Shum, P W; Basu, A et al. (1991) Synthesis of structural analogues of lyngbyatoxin A and their evaluation as activators of protein kinase C. J Med Chem 34:2420-30
Powis, G; Aksoy, I A; Melder, D C et al. (1991) D-3-deoxy-3-substituted myo-inositol analogues as inhibitors of cell growth. Cancer Chemother Pharmacol 29:95-104
Basu, A; Kozikowski, A P; Sato, K et al. (1991) Cellular sensitization to cis-diamminedichloroplatinum(II) by novel analogues of the protein kinase C activator lyngbyatoxin A. Cancer Res 51:2511-4