Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA050183-05
Application #
2093638
Study Section
Special Emphasis Panel (SRC (52))
Project Start
1990-09-01
Project End
1997-08-31
Budget Start
1994-09-01
Budget End
1997-08-31
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Rutgers University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Park, Jun Hyoung; Vithayathil, Sajna; Kumar, Santosh et al. (2016) Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer. Cell Rep 14:2154-2165
Vadakkan, Tegy J; Landua, John D; Bu, Wen et al. (2014) Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer. Stem Cells Transl Med 3:857-66
Zhang, Xiaomei; Claerhout, Sofie; Prat, Aleix et al. (2013) A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res 73:4885-97
Iyer, Vandana; Klebba, Ina; McCready, Jessica et al. (2012) Estrogen promotes ER-negative tumor growth and angiogenesis through mobilization of bone marrow-derived monocytes. Cancer Res 72:2705-13
Creighton, Chad J; Sada, Yvonne H; Zhang, Yiqun et al. (2012) A gene transcription signature of obesity in breast cancer. Breast Cancer Res Treat 132:993-1000
Dave, Bhuvanesh; Migliaccio, Ilenia; Gutierrez, M Carolina et al. (2011) Loss of phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers. J Clin Oncol 29:166-73
Creighton, Chad J; Chang, Jenny C; Rosen, Jeffrey M (2010) Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. J Mammary Gland Biol Neoplasia 15:253-60
Yang, Wei Tse; Lewis, Michael T; Hess, Kenneth et al. (2010) Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density. Breast Cancer Res Treat 119:305-14
Creighton, Chad J; Li, Xiaoxian; Landis, Melissa et al. (2009) Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A 106:13820-5
Zhang, Xiaomei; Harrington, Nikesha; Moraes, Ricardo C et al. (2009) Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo). Breast Cancer Res Treat 115:505-21

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