Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA050443-02
Application #
3194919
Study Section
Pathology B Study Section (PTHB)
Project Start
1989-07-01
Project End
1993-04-30
Budget Start
1990-05-01
Budget End
1991-04-30
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
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Lessnick, S L; Braun, B S; Denny, C T et al. (1995) Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene. Oncogene 10:423-31
Wood Jr, W J; Thompson, A A; Korenberg, J et al. (1993) Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB). Genomics 16:187-92
May, W A; Gishizky, M L; Lessnick, S L et al. (1993) Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proc Natl Acad Sci U S A 90:5752-6
May, W A; Lessnick, S L; Braun, B S et al. (1993) The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Mol Cell Biol 13:7393-8