Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA050677-07
Application #
2093927
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1989-03-02
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Cedars Healthcare Group, Ltd
Department
Type
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33136
Frankfurt, O S; Robb, J A; Sugarbaker, E V et al. (1997) Apoptosis in breast carcinomas detected with monoclonal antibody to single-stranded DNA: relation to bcl-2 expression, hormone receptors, and lymph node metastases. Clin Cancer Res 3:465-71
Frankfurt, O S; Robb, J A; Sugarbaker, E V et al. (1996) Apoptosis in human breast and gastrointestinal carcinomas. Detection in histological sections with monoclonal antibody to single-stranded DNA. Anticancer Res 16:1979-88
Frankfurt, O S; Robb, J A; Sugarbaker, E V et al. (1996) Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis. Exp Cell Res 226:387-97
Frankfurt, O S; Sugarbaker, E V; Robb, J A et al. (1995) Synergistic induction of apoptosis in breast cancer cells by tamoxifen and calmodulin inhibitors. Cancer Lett 97:149-54
Frankfurt, O S (1994) Detection of apoptosis in leukemic and breast cancer cells with monoclonal antibody to single-stranded DNA. Anticancer Res 14:1861-9
Frankfurt, O S; Seckinger, D; Sugarbaker, E V (1994) Pleiotropic drug resistance and survival advantage in leukemic cells with diminished apoptotic response. Int J Cancer 59:217-24
Frankfurt, O S; Byrnes, J J; Seckinger, D et al. (1993) Apoptosis (programmed cell death) and the evaluation of chemosensitivity in chronic lymphocytic leukemia and lymphoma. Oncol Res 5:37-42
Frankfurt, O S; Seckinger, D; Sugarbaker, E V (1993) Inhibition of DNA repair in cells treated with a combination of alkylating agents. Anticancer Res 13:947-52
Frankfurt, O S; Seckinger, D; Sugarbaker, E V (1991) Intercellular transfer of drug resistance. Cancer Res 51:1190-5
Frankfurt, O S (1991) Inhibition of DNA repair and the enhancement of cytotoxicity of alkylating agents. Int J Cancer 48:916-23

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