Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA051001-06A1
Application #
2094057
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1990-04-01
Project End
2000-12-31
Budget Start
1996-03-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

Pauley, Jennifer L; Panetta, John C; Crews, Kristine R et al. (2013) Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments. Cancer Chemother Pharmacol 72:369-78
Pui, C H; Pei, D; Sandlund, J T et al. (2010) Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia. Leukemia 24:371-82
Crews, Kristine R; Zhou, Yinmei; Pauley, Jennifer L et al. (2010) Effect of allopurinol versus urate oxidase on methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia. Cancer 116:227-32
Morris, Van K; Spraker, Holly L; Howard, Scott C et al. (2010) Severe thrombocytopenia with iron deficiency anemia. Pediatr Hematol Oncol 27:413-9
Pottier, N; Paugh, S W; Ding, C et al. (2010) Promoter polymorphisms in the ?-2 adrenergic receptor are associated with drug-induced gene expression changes and response in acute lymphoblastic leukemia. Clin Pharmacol Ther 88:854-61
Metzger, Monika L; Hudson, Melissa M; Krasin, Matthew J et al. (2010) Initial response to salvage therapy determines prognosis in relapsed pediatric Hodgkin lymphoma patients. Cancer 116:4376-84
Treviño, Lisa R; Shimasaki, Noriko; Yang, Wenjian et al. (2009) Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J Clin Oncol 27:5972-8
Pui, Ching-Hon; Campana, Dario; Pei, Deqing et al. (2009) Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med 360:2730-41
Panetta, J C; Gajjar, A; Hijiya, N et al. (2009) Comparison of native E. coli and PEG asparaginase pharmacokinetics and pharmacodynamics in pediatric acute lymphoblastic leukemia. Clin Pharmacol Ther 86:651-8
French, Deborah; Yang, Wenjian; Cheng, Cheng et al. (2009) Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia. Blood 113:4512-20

Showing the most recent 10 out of 31 publications