Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA051161-03
Application #
3195876
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1991-06-01
Project End
1994-05-31
Budget Start
1992-11-01
Budget End
1993-05-31
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Borchardt, P E; Quadri, S M; Freedman, R S et al. (2000) Intraperitoneal radioimmunotherapy with human monoclonal IGM in nude mice with peritoneal carcinomatosis. Cancer Biother Radiopharm 15:53-64
Quadri, S M; Vriesendorp, H M (1998) Effects of linker chemistry on the pharmacokinetics of radioimmunoconjugates. Q J Nucl Med 42:250-61
Borchardt, P E; Quadri, S M; Freedman, R S et al. (1998) Indium-111- and yttrium-90-labeled human monoclonal immunoglobulin M targeting of human ovarian cancer in mice. J Nucl Med 39:476-84
Vriesendorp, F J; Quadri, S M; Flynn, R E et al. (1997) Preclinical analysis of radiolabeled anti-GD2 immunoglobulin G. Cancer 80:2642-9
Borchardt, P E; Quadri, S M; Freedman, R S et al. (1997) Intralesional radiolabeled human monoclonal IgM in human tumor xenografts. Radiother Oncol 44:283-93
Vriesendorp, H M; Quadri, S M; Jaeckle, K A et al. (1996) Proposal for translational analysis and development of clinical radiolabeled immunoglobulin therapy. Radiother Oncol 41:151-61
Quadri, S M; Malik, A B; Chu, H B et al. (1996) Intraperitoneal indium-111- and yttrium-90-labeled human IgM (AC6C3-2B12) in nude mice bearing peritoneal carcinomatosis. J Nucl Med 37:1545-51
Ali, M S; Quadri, S M (1996) Maleimido derivatives of diethylenetriaminepentaacetic acid and triethylenetetraaminehexaacetic acid: their synthesis and potential for specific conjugation with biomolecules. Bioconjug Chem 7:576-83
Vriesendorp, H M; Morton, J D; Quadri, S M (1995) Review of five consecutive studies of radiolabeled immunoglobulin therapy in Hodgkin's disease. Cancer Res 55:5888s-5892s
Quadri, S M; Siddiqui, A; Klein, J L et al. (1995) Biodistribution and tumor localization of 111In-labeled unmodified and modified F(ab')2 fragments of human monoclonal IgM (16.88) in a nude mouse model. Nucl Med Biol 22:413-23

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