Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA051982-06A2
Application #
2094500
Study Section
Virology Study Section (VR)
Project Start
1989-08-01
Project End
2000-01-31
Budget Start
1996-04-01
Budget End
1997-01-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Eastern Virginia Medical School
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Norfolk
State
VA
Country
United States
Zip Code
23501
Briggs, Joseph; Chamboredon, Sandrine; Castellazzi, Marc et al. (2002) Transcriptional upregulation of SPARC, in response to c-Jun overexpression, contributes to increased motility and invasion of MCF7 breast cancer cells. Oncogene 21:7077-91
Rinehart-Kim, J; Johnston, M; Birrer, M et al. (2000) Alterations in the gene expression profile of MCF-7 breast tumor cells in response to c-Jun. Int J Cancer 88:180-90
Sehgal, A; Briggs, J; Rinehart-Kim, J et al. (2000) The chicken c-Jun 5' untranslated region directs translation by internal initiation. Oncogene 19:2836-45
Basso, J; Briggs, J; Findlay, C et al. (2000) Directed mutation of the basic domain of v-Jun alters DNA binding specificity and abolishes its oncogenic activity in chicken embryo fibroblasts. Oncogene 19:4876-85
Bos, T J; Margiotta, P; Bush, L et al. (1999) Enhanced cell motility and invasion of chicken embryo fibroblasts in response to Jun over-expression. Int J Cancer 81:404-10
Hadman, M; Lin, W; Bush, L et al. (1998) Apolipoprotein A-1 is a negative target of v-Jun overexpression. Oncogene 16:655-60