Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA052178-05
Application #
2094637
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1990-05-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Natarajan, Karthika; Xie, Yi; Baer, Maria R et al. (2012) Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance. Biochem Pharmacol 83:1084-103
Bauer, Kenneth S; Karp, Judith E; Garimella, Tushar S et al. (2005) A phase I and pharmacologic study of idarubicin, cytarabine, etoposide, and the multidrug resistance protein (MDR1/Pgp) inhibitor PSC-833 in patients with refractory leukemia. Leuk Res 29:263-71
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Doyle, L A; Yang, W; Abruzzo, L V et al. (1998) A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci U S A 95:15665-70
Ross, D D; Gao, Y; Yang, W et al. (1997) The 95-kilodalton membrane glycoprotein overexpressed in novel multidrug-resistant breast cancer cells is NCA, the nonspecific cross-reacting antigen of carcinoembryonic antigen. Cancer Res 57:5460-4
Doyle, L A; Yang, W; Rishi, A K et al. (1996) H19 gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein. Cancer Res 56:2904-7
Ross, D D; Doyle, L A; Yang, W et al. (1995) Susceptibility of idarubicin, daunorubicin, and their C-13 alcohol metabolites to transport-mediated multidrug resistance. Biochem Pharmacol 50:1673-83
Doyle, L A; Ross, D D; Sridhara, R et al. (1995) Expression of a 95 kDa membrane protein is associated with low daunorubicin accumulation in leukaemic blast cells. Br J Cancer 71:52-8
Doyle, L A (1994) Topoisomerase expression in cancer cell lines and clinical samples. Cancer Chemother Pharmacol 34 Suppl:S32-40

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