Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA052308-03
Application #
3197102
Study Section
Experimental Immunology Study Section (EI)
Project Start
1991-07-01
Project End
1994-06-30
Budget Start
1993-01-01
Budget End
1993-06-30
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Temple University
Department
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Platsoucas, Chris D; Fincke, John E; Pappas, John et al. (2003) Immune responses to human tumors: development of tumor vaccines. Anticancer Res 23:1969-96
Kooi, S; Zhang, H Z; Patenia, R et al. (1996) HLA class I expression on human ovarian carcinoma cells correlates with T-cell infiltration in vivo and T-cell expansion in vitro in low concentrations of recombinant interleukin-2. Cell Immunol 174:116-28
Freedman, R S; Platsoucas, C D (1996) Immunotherapy for peritoneal ovarian carcinoma metastasis using ex vivo expanded tumor infiltrating lymphocytes. Cancer Treat Res 82:115-46
Nash, M A; Platsoucas, C D; Wong, B Y et al. (1995) Transduction of rIL-2 expanded CD4+ and CD8+ ovarian TIL-derived T cell lines with the G1Na (neor) replication-deficient retroviral vector. Hum Gene Ther 6:1379-89
Freedman, R S; Tomasovic, B; Templin, S et al. (1994) Large-scale expansion in interleukin-2 of tumor-infiltrating lymphocytes from patients with ovarian carcinoma for adoptive immunotherapy. J Immunol Methods 167:145-60
Lee, J E; Reveille, J D; Ross, M I et al. (1994) HLA-DQB1*0301 association with increased cutaneous melanoma risk. Int J Cancer 59:510-3
Chen, P F; Freedman, R S; Chernajovsky, Y et al. (1994) Amplification of immunoglobulin transcripts by the non-palindromic adaptor polymerase chain reaction (NPA-PCR). Nucleotide sequence analysis of two human monoclonal antibodies recognizing two cell surface antigens expressed in ovarian, cervix, breast, col Hum Antibodies Hybridomas 5:131-42
Mitropoulos, D; Kooi, S; Rodriguez-Villanueva, J et al. (1994) Characterization of fresh (uncultured) tumour-infiltrating lymphocytes (TIL) and TIL-derived T cell lines from patients with renal cell carcinoma. Clin Exp Immunol 97:321-7
Mathioudakis, G; Chen, P F; Li, Y D et al. (1993) Preferential rearrangements of the V gamma I subgroup of the gamma-chain of the T-cell antigen receptor to J gamma 2C gamma 2 gene segments in peripheral blood lymphocyte transcripts from normal donors. Scand J Immunol 38:31-6
Kooi, S; Freedman, R S; Rodriguez-Villanueva, J et al. (1993) Cytokine production by T-cell lines derived from tumor-infiltrating lymphocytes from patients with ovarian carcinoma: tumor-specific immune responses and inhibition of antigen-independent cytokine production by ovarian tumor cells. Lymphokine Cytokine Res 12:429-37

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