Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA053453-05
Application #
2095331
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1991-01-01
Project End
1996-12-31
Budget Start
1995-01-01
Budget End
1996-12-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Pathology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Eagon, P K; Teepe, A G; Elm, M S et al. (1999) Hepatic hyperplasia and cancer in rats: alterations in copper metabolism. Carcinogenesis 20:1091-6
Rao, K N; Elm, M S; Kelly, R H et al. (1997) Hepatic hyperplasia and cancer in rats: metabolic alterations associated with cell growth. Gastroenterology 113:238-48
Menegazzi, M; Carcereri-De Prati, A; Suzuki, H et al. (1997) Liver cell proliferation induced by nafenopin and cyproterone acetate is not associated with increases in activation of transcription factors NF-kappaB and AP-1 or with expression of tumor necrosis factor alpha. Hepatology 25:585-92
Columbano, A; Ledda-Columbano, G M; Pibiri, M et al. (1997) Increased expression of c-fos, c-jun and LRF-1 is not required for in vivo priming of hepatocytes by the mitogen TCPOBOP. Oncogene 14:857-63
Ohmura, T; Katyal, S L; Locker, J et al. (1997) Induction of cellular DNA synthesis in the pancreas and kidneys of rats by peroxisome proliferators, 9-cis retinoic acid, and 3,3',5-triiodo-L-thyronine. Cancer Res 57:795-8
Eagon, P K; Elm, M S; Epley, M J et al. (1996) Sex steroid metabolism and receptor status in hepatic hyperplasia and cancer in rats. Gastroenterology 110:1199-207
Shinozuka, H; Ohmura, T; Katyal, S L et al. (1996) Possible roles of nonparenchymal cells in hepatocyte proliferation induced by lead nitrate and by tumor necrosis factor alpha. Hepatology 23:1572-7
Ohmura, T; Columbano, G L; Columbano, A et al. (1996) 9-cis retinoic acid is a direct hepatocyte mitogen in rats. Life Sci 58:PL211-216
Ohmura, T; Ledda-Columbano, G M; Piga, R et al. (1996) Hepatocyte proliferation induced by a single dose of a peroxisome proliferator. Am J Pathol 148:815-24
Columbano, A; Shinozuka, H (1996) Liver regeneration versus direct hyperplasia. FASEB J 10:1118-28

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