Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA054298-03S1
Application #
3198804
Study Section
Pathology B Study Section (PTHB)
Project Start
1991-04-01
Project End
1996-03-31
Budget Start
1993-06-18
Budget End
1994-03-31
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037

  Publications

Voice, J K; Klemke, R L; Le, A et al. (1999) Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility. J Biol Chem 274:17164-70
Knaus, U G; Wang, Y; Reilly, A M et al. (1998) Structural requirements for PAK activation by Rac GTPases. J Biol Chem 273:21512-8
Jones, M K; Jackson, J H (1998) Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo. J Biol Chem 273:1782-7
Jackson, J H; Vollenweider, M; Hill, J et al. (1997) Stimulated human leukocytes cause activating mutations in the K-ras protooncogene. Oncogene 14:2803-8
Jackson, J H (1994) Potential molecular mechanisms of oxidant-induced carcinogenesis. Environ Health Perspect 102 Suppl 10:155-7
Jackson, J H; Li, J W; Buss, J E et al. (1994) Polylysine domain of K-ras 4B protein is crucial for malignant transformation. Proc Natl Acad Sci U S A 91:12730-4