Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA054337-06
Application #
2095832
Study Section
Molecular Biology Study Section (MBY)
Project Start
1991-05-01
Project End
2001-04-30
Budget Start
1996-08-15
Budget End
1997-04-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109
Lorincz, Matthew C; Schubeler, Dirk; Hutchinson, Shauna R et al. (2002) DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a/b-independent de novo methylation. Mol Cell Biol 22:7572-80
Tsuji, K; Kraut, N; Groudine, M et al. (2001) Vitamin D(3) enhances the expression of I-mfa, an inhibitor of the MyoD family, in osteoblasts. Biochim Biophys Acta 1539:122-30
Cimbora, D M; Schubeler, D; Reik, A et al. (2000) Long-distance control of origin choice and replication timing in the human beta-globin locus are independent of the locus control region. Mol Cell Biol 20:5581-91
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Wu, D Y; Krumm, A; Schubach, W H (2000) Promoter-specific targeting of human SWI-SNF complex by Epstein-Barr virus nuclear protein 2. J Virol 74:8893-903
Bulger, M; Groudine, M (1999) Looping versus linking: toward a model for long-distance gene activation. Genes Dev 13:2465-77
Kraut, N; Snider, L; Chen, C M et al. (1998) Requirement of the mouse I-mfa gene for placental development and skeletal patterning. EMBO J 17:6276-88
Reik, A; Telling, A; Zitnik, G et al. (1998) The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells. Mol Cell Biol 18:5992-6000
Seibler, J; Schubeler, D; Fiering, S et al. (1998) DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs. Biochemistry 37:6229-34
Madisen, L; Krumm, A; Hebbes, T R et al. (1998) The immunoglobulin heavy chain locus control region increases histone acetylation along linked c-myc genes. Mol Cell Biol 18:6281-92

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