Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA054816-04A2
Application #
2096173
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1992-04-01
Project End
2000-04-30
Budget Start
1996-07-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
Tang, Qian; Staub, Cory M; Gao, Guofeng et al. (2002) A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein. Mol Biol Cell 13:4484-96
Yue, J; Mulder, K M (2001) Transforming growth factor-beta signal transduction in epithelial cells. Pharmacol Ther 91:1-34
Yue, J; Mulder, K M (2000) Requirement of Ras/MAPK pathway activation by transforming growth factor beta for transforming growth factor beta 1 production in a Smad-dependent pathway. J Biol Chem 275:30765-73
Yue, J; Mulder, K M (2000) Activation of the mitogen-activated protein kinase pathway by transforming growth factor-beta. Methods Mol Biol 142:125-31
Mulder, K M (2000) Role of Ras and Mapks in TGFbeta signaling. Cytokine Growth Factor Rev 11:23-35
Yue, J; Hartsough, M T; Frey, R S et al. (1999) Cloning and expression of a rat Smad1: regulation by TGFbeta and modulation by the Ras/MEK pathway. J Cell Physiol 178:387-96
Yue, J; Frey, R S; Mulder, K M (1999) Cross-talk between the Smad1 and Ras/MEK signaling pathways for TGFbeta. Oncogene 18:2033-7
Liu, X; Yue, J; Frey, R S et al. (1998) Transforming growth factor beta signaling through Smad1 in human breast cancer cells. Cancer Res 58:4752-7
Yue, J; Buard, A; Mulder, K M (1998) Blockade of TGFbeta3 up-regulation of p27Kip1 and p21Cip1 by expression of RasN17 in epithelial cells. Oncogene 17:47-55
Hartsough, M T; Mulder, K M (1997) Transforming growth factor-beta signaling in epithelial cells. Pharmacol Ther 75:21-41

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