Tumor Necrosis Factor and T-Cell Development

Stutman, Osias

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA055068-05
• Application #: 2096312
• Study Section: Immunobiology Study Section (IMB)
• Project Start: 1992-04-13
• Project End: 1998-01-31
• Budget Start: 1996-02-01
• Budget End: 1998-01-31
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: Sloan-Kettering Institute for Cancer Research
• DUNS #: 064931884
• City: New York
• State: NY
• Country: United States
• Zip Code: 10065

Publications

Baseta, J G; Stutman, O (2000) TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset. J Immunol 165:5621-30

Glickstein, L; Macphail, S; Stutman, O (1996) Uncoupling IL-2 production from apoptosis and TNF production by changing the signal through the TCR. J Immunol 156:2062-7

Shih, S C; Stutman, O (1996) Cell cycle-dependent tumor necrosis factor apoptosis. Cancer Res 56:1591-8

Hernandez-Caselles, T; Stutman, O (1993) Immune functions of tumor necrosis factor. I. Tumor necrosis factor induces apoptosis of mouse thymocytes and can also stimulate or inhibit IL-6-induced proliferation depending on the concentration of mitogenic costimulation. J Immunol 151:3999-4012