|
Kingston, D G; Chaudhary, A G; Chordia, M D et al. (1998) Synthesis and biological evaluation of 2-acyl analogues of paclitaxel (Taxol). J Med Chem 41:3715-26
|
|
Han, Y; Malak, H; Chaudhary, A G et al. (1998) Distances between the paclitaxel, colchicine, and exchangeable GTP binding sites on tubulin. Biochemistry 37:6636-44
|
|
Watson, J M; Kingston, D G; Chordia, M D et al. (1998) Identification of the structural region of taxol that may be responsible for cytokine gene induction and cytotoxicity in human ovarian cancer cells. Cancer Chemother Pharmacol 41:391-7
|
|
Chordia, M D; Kingston, D G; Hamel, E et al. (1997) Synthesis and biological activity of A-nor-paclitaxel analogues. Bioorg Med Chem 5:941-7
|
|
Han, Y; Chaudhary, A G; Chordia, M D et al. (1996) Interaction of a fluorescent derivative of paclitaxel (Taxol) with microtubules and tubulin-colchicine. Biochemistry 35:14173-83
|
|
Pengsuparp, T; Kingston, D G; Neidigh, K A et al. (1996) Evaluation of the cytotoxic mechanism mediated by baccatin III, the synthetic precursor of taxol. Chem Biol Interact 101:103-14
|
|
Grover, S; Rimoldi, J M; Molinero, A A et al. (1995) Differential effects of paclitaxel (Taxol) analogs modified at positions C-2, C-7, and C-3' on tubulin polymerization and polymer stabilization: identification of a hyperactive paclitaxel derivative. Biochemistry 34:3927-34
|
|
Chen, R; Kingston, D G (1994) Isolation and structure elucidation of new taxoids from Taxus brevifolia. J Nat Prod 57:1017-21
|
|
Samaranayake, G; Neidigh, K A; Kingston, D G (1993) Modified taxols, 8. Deacylation and reacylation of baccatin III. J Nat Prod 56:884-98
|
|
Liang, J; Kingston, D G (1993) Two new taxane diterpenoids from Taxus mairei. J Nat Prod 56:594-9
|
