Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA055300-06
Application #
2096515
Study Section
Radiation Study Section (RAD)
Project Start
1992-08-17
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1998-05-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Pero, R W; Axelsson, B; Siemann, D et al. (1999) Newly discovered anti-inflammatory properties of the benzamides and nicotinamides. Mol Cell Biochem 193:119-25
Mendenhall, W M; Parsons, J T; Siemann, D W (1996) Does neck stage predict local control after irradiation for head and neck cancer? Oncology (Williston Park) 10:381-4;discussion: 384-96
Fenton, B M; Siemann, D W (1995) Are direct measures of tumor oxygenation reflective of changes in tumor radiosensitivity following oxygen manipulation? Acta Oncol 34:307-11
Fenton, B M (1995) The effects of carbogen and nicotinamide on intravascular oxyhaemoglobin saturations in SCCVII and KHT murine tumours. Br J Cancer 71:945-9
Siemann, D W; Horsman, M R; Chaplin, D J (1994) The radiation response of KHT sarcomas following nicotinamide treatment and carbogen breathing. Radiother Oncol 31:117-22
Fenton, B M; Siemann, D W (1994) Investigations of perfusion-limited hypoxia and oxygenation in the KHT sarcoma. Adv Exp Med Biol 361:627-34
Horsman, M R; Khalil, A A; Siemann, D W et al. (1994) Relationship between radiobiological hypoxia in tumors and electrode measurements of tumor oxygenation. Int J Radiat Oncol Biol Phys 29:439-42
Horsman, M R; Siemann, D W; Nordsmark, M et al. (1994) The combination of nicotinamide and carbogen breathing to improve tumour oxygenation prior to radiation treatment. Adv Exp Med Biol 361:635-42
Fenton, B M; Boyce, D J (1994) Micro-regional mapping of HbO2 saturations and blood flow following nicotinamide administration. Int J Radiat Oncol Biol Phys 29:459-62
Chaplin, D J; Horsman, M R; Siemann, D W (1993) Further evaluation of nicotinamide and carbogen as a strategy to reoxygenate hypoxic cells in vivo: importance of nicotinamide dose and pre-irradiation breathing time. Br J Cancer 68:269-73