Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA056072-02
Application #
3200562
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1992-04-15
Project End
1997-03-31
Budget Start
1993-06-10
Budget End
1994-03-31
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of South Florida
Department
Type
Schools of Medicine
DUNS #
City
Tampa
State
FL
Country
United States
Zip Code
33612
Liu, R Y; Fan, C; Olashaw, N E et al. (1999) Tumor necrosis factor-alpha-induced proliferation of human Mo7e leukemic cells occurs via activation of nuclear factor kappaB transcription factor. J Biol Chem 274:13877-85
Hu, X; Moscinski, L C; Zuckerman, K S (1999) Transforming growth factor beta inhibits growth of more differentiated myeloid leukemia cells and retinoblastoma protein phosphorylation at serine 795. Exp Hematol 27:605-14
Hu, X; Tang, M; Fisher, A B et al. (1999) TNF-alpha-induced growth suppression of CD34+ myeloid leukemic cell lines signals through TNF receptor type I and is associated with NF-kappa B activation. J Immunol 163:3106-15
Liu, R Y; Fan, C; Garcia, R et al. (1999) Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines. Blood 93:2369-79
Hu, X; Zuckerman, K S (1998) Cloning and sequencing of an alternative splicing-derived cDNA variant of the GM-CSF receptor alpha subunit, which encodes a truncated protein. Am J Hematol 58:145-7
Liu, R Y; Fan, C; Mitchell, S et al. (1998) The role of type I and type II tumor necrosis factor (TNF) receptors in the ability of TNF-alpha to transduce a proliferative signal in the human megakaryoblastic leukemic cell line Mo7e. Cancer Res 58:2217-23
Hu, X; Zucherman, K S (1996) Removing Monolayer cells from culture dishes by incubation with EDTA in studies of cell surface receptors. Biotechniques 21:784, 786
Busque, L; Gilliland, D G; Prchal, J T et al. (1995) Clonality in juvenile chronic myelogenous leukemia. Blood 85:21-30
Hu, X; Emanuel, P D; Zuckerman, K S (1994) Cloning and sequencing of the cDNAs encoding two alternative splicing-derived variants of the alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor. Biochim Biophys Acta 1223:306-8