Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA056103-05
Application #
2097100
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1991-06-01
Project End
1996-11-30
Budget Start
1995-06-01
Budget End
1996-11-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Genetics
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Cascio, Sandra; Faylo, Jacque L; Sciurba, Joshua C et al. (2017) Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-?B p65 and EzH2, in colitis-associated cancer. Oncotarget 8:105284-105298
Lohmueller, Jason J; Sato, Shuji; Popova, Lana et al. (2016) Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential. Sci Rep 6:31740
Finn, Olivera J; Beatty, Pamela L (2016) Cancer immunoprevention. Curr Opin Immunol 39:52-8
Finn, Olivera J; Khleif, Samir N; Herberman, Ronald B (2015) The FDA guidance on therapeutic cancer vaccines: the need for revision to include preventive cancer vaccines or for a new guidance dedicated to them. Cancer Prev Res (Phila) 8:1011-6
Marvel, Douglas M; Finn, Olivera J (2014) Global Inhibition of DC Priming Capacity in the Spleen of Self-Antigen Vaccinated Mice Requires IL-10. Front Immunol 5:59
Finn, Olivera J (2014) Vaccines for cancer prevention: a practical and feasible approach to the cancer epidemic. Cancer Immunol Res 2:708-13
Iheagwara, Uzoma K; Beatty, Pamela L; Van, Phu T et al. (2014) Influenza virus infection elicits protective antibodies and T cells specific for host cell antigens also expressed as tumor-associated antigens: a new view of cancer immunosurveillance. Cancer Immunol Res 2:263-73
Zhang, Lixin; Vlad, Anda; Milcarek, Christine et al. (2013) Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms. Cancer Immunol Immunother 62:423-35
Cascio, Sandra; Farkas, Adam M; Hughey, Rebecca P et al. (2013) Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration. Oncotarget 4:1686-97
Reichenbach, Dawn K; Finn, Olivera J (2013) Early in vivo signaling profiles in MUC1-specific CD4(+) T cells responding to two different MUC1-targeting vaccines in two different microenvironments. Oncoimmunology 2:e23429

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