Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA056295-01
Application #
3200693
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1991-12-05
Project End
1995-11-30
Budget Start
1991-12-05
Budget End
1992-11-30
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Ohio State University
Department
Type
Schools of Veterinary Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Buck, W R; Podell, M (1998) Neuronal loss in FIV-MD infected cats. J NeuroAIDS 2:69-77
Mathes, L E; Hayes, K A; Kociba, G (1996) Evidence that high-dosage zidovudine at time of retrovirus exposure reduces antiviral efficacy. Antimicrob Agents Chemother 40:2183-6
Hayes, K A; Wilkinson, J G; Frick, R et al. (1995) Early suppression of viremia by ZDV does not alter the spread of feline immunodeficiency virus infection in cats. J Acquir Immune Defic Syndr Hum Retrovirol 9:114-22
Mukherji, E; Au, J L; Mathes, L E (1994) Differential antiviral activities and intracellular metabolism of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine in human cells. Antimicrob Agents Chemother 38:1573-9
Tochikura, T S; Tanabe-Tochikura, A; Hayes, K A et al. (1993) Fusion activity dissociated from replication ability in feline immunodeficiency virus (FIV) in human cells. J Acquir Immune Defic Syndr 6:1301-10
Hanlon, M A; Marr, J M; Hayes, K A et al. (1993) Loss of neutrophil and natural killer cell function following feline immunodeficiency virus infection. Viral Immunol 6:119-24
Hayes, K A; Lafrado, L J; Erickson, J G et al. (1993) Prophylactic ZDV therapy prevents early viremia and lymphocyte decline but not primary infection in feline immunodeficiency virus-inoculated cats. J Acquir Immune Defic Syndr 6:127-34
Podell, M; Oglesbee, M; Mathes, L et al. (1993) AIDS-associated encephalopathy with experimental feline immunodeficiency virus infection. J Acquir Immune Defic Syndr 6:758-71
Tanabe-Tochikura, A; Tochikura, T S; Blakeslee Jr, J R et al. (1992) Anti-human immunodeficiency virus (HIV) agents are also potent and selective inhibitors of feline immunodeficiency virus (FIV)-induced cytopathic effect: development of a new method for screening of anti-FIV substances in vitro. Antiviral Res 19:161-72
Mathes, L E; Polas, P J; Hayes, K A et al. (1992) Pre- and postexposure chemoprophylaxis: evidence that 3'-azido-3'-dideoxythymidine inhibits feline leukemia virus disease by a drug-induced vaccine response. Antimicrob Agents Chemother 36:2715-21