|
Balachandran, R; Grant, S G; Welsh, M J et al. (2000) Z-1,1-Dichloro-2,3-diphenylcyclopropanes block human prostate carcinoma cell proliferation, inhibit prostate-specific antigen expression, and initiate apoptosis. Prostate 45:277-88
|
|
Balachandran, R; ter Haar, E; Yalowich, J C et al. (1999) Induction of human breast cancer cell apoptosis from G2/M preceded by stimulation into the cell cycle by Z-1,1-dichloro-2,3-diphenylcyclopropane. Biochem Pharmacol 57:97-110
|
|
Balachandran, R; ter Haar, E; Welsh, M J et al. (1998) The potent microtubule-stabilizing agent (+)-discodermolide induces apoptosis in human breast carcinoma cells--preliminary comparisons to paclitaxel. Anticancer Drugs 9:67-76
|
|
Tyurin, V A; Tyurina, Y Y; Quinn, P J et al. (1998) Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfection. Brain Res Mol Brain Res 60:270-81
|
|
ter Haar, E; Hamel, E; Balachandran, R et al. (1997) Cellular targets of the anti-breast cancer agent Z-1,1-dichloro-2,3-diphenylcyclopropane: type II estrogen binding sites and tubulin. Anticancer Res 17:1861-9
|
|
Jonnalagadda, S S; ter Haar, E; Hamel, E et al. (1997) Synthesis and biological evaluation of 1,1-dichloro-2,3-diarylcyclopropanes as antitubulin and anti-breast cancer agents. Bioorg Med Chem 5:715-22
|
|
ter Haar, E; Day, B W (1996) Cytostatic and cytotoxic action of Z-1, 1-dichloro-2,3-diphenylcyclopropane in three human breast cancer cell lines. Anticancer Res 16:1107-15
|
|
ter Haar, E; Rosenkranz, H S; Hamel, E et al. (1996) Computational and molecular modeling evaluation of the structural basis for tubulin polymerization inhibition by colchicine site agents. Bioorg Med Chem 4:1659-71
|
|
Stoyanovosky, D A; Goldman, R; Jonnalagadda, S S et al. (1996) Detection and characterization of the electron paramagnetic resonance-silent glutathionyl-5,5-dimethyl-1-pyrroline N-oxide adduct derived from redox cycling of phenoxyl radicals in model systems and HL-60 cells. Arch Biochem Biophys 330:3-11
|
