Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA057592-03A2
Application #
2098315
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1992-08-01
Project End
1999-12-31
Budget Start
1996-03-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Texas A&M University
Department
Biology
Type
Schools of Earth Sciences/Natur
DUNS #
City
College Station
State
TX
Country
United States
Zip Code
77845
Lu, Hua; Gorman, Elizabeth; McKnight, Thomas D (2005) Molecular characterization of two anthranilate synthase alpha subunit genes in Camptotheca acuminata. Planta 221:352-60
Lorence, Argelia; Nessler, Craig L (2004) Camptothecin, over four decades of surprising findings. Phytochemistry 65:2735-49
Lorence, A; Medina-Bolivar, F; Nessler, C L (2004) Camptothecin and 10-hydroxycamptothecin from Camptotheca acuminata hairy roots. Plant Cell Rep 22:437-41
Vincent, R M; Lopez-Meyer, M; McKnight, T D et al. (1997) Sustained harvest of camptothecin from the leaves of Camptotheca acuminata. J Nat Prod 60:618-9
Lopez-Meyer, M; Nessler, C L (1997) Tryptophan decarboxylase is encoded by two autonomously regulated genes in Camptotheca acuminata which are differentially expressed during development and stress. Plant J 11:1167-75
Maldonado-Mendoza, I E; Nessler, C L (1997) Molecular characterization of the AP19 gene family in Arabidopsis thaliana: components of the Golgi AP-1 clathrin assembly protein complex. Plant Mol Biol 35:865-72
Maldonado-Mendoza, I E; Vincent, R M; Nessler, C L (1997) Molecular characterization of three differentially expressed members of the Camptotheca acuminata 3-hydroxy-3-methylglutaryl CoA reductase (HMGR) gene family. Plant Mol Biol 34:781-90
Maldonado-Mendoza, I E; Lopez-Meyer, M; Galef, J R et al. (1996) Molecular analysis of a new member of the opium poppy tyrosine/3,4-dihydroxyphenylalanine decarboxylase gene family. Plant Physiol 110:43-9
Nessler, C L (1994) Metabolic engineering of plant secondary products. Transgenic Res 3:109-15
Lopez-Meyer, M; Nessler, C L; McKnight, T D (1994) Sites of accumulation of the antitumor alkaloid camptothecin in Camptotheca acuminata. Planta Med 60:558-60

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