Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA057904-05
Application #
2098625
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1992-09-01
Project End
1997-09-09
Budget Start
1996-07-01
Budget End
1997-09-09
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Merger, M; Viney, J L; Borojevic, R et al. (2002) Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine. Gut 51:155-63
Jiang, Z; Podack, E; Levy, R B (2001) Major histocompatibility complex-mismatched allogeneic bone marrow transplantation using perforin and/or Fas ligand double-defective CD4(+) donor T cells: involvement of cytotoxic function by donor lymphocytes prior to graft-versus-host disease pathogenes Blood 98:390-7
Muta, H; Boise, L H; Fang, L et al. (2000) CD30 signals integrate expression of cytotoxic effector molecules, lymphocyte trafficking signals, and signals for proliferation and apoptosis. J Immunol 165:5105-11
Podack, E R (1999) How to induce involuntary suicide: the need for dipeptidyl peptidase I. Proc Natl Acad Sci U S A 96:8312-4
Lee, R K; Cai, J P; Deyev, V et al. (1999) Azidothymidine and interferon-alpha induce apoptosis in herpesvirus-associated lymphomas. Cancer Res 59:5514-20
Yamazaki, K; Spruill, G; Rhoderick, J et al. (1999) Small cell lung carcinomas express shared and private tumor antigens presented by HLA-A1 or HLA-A2. Cancer Res 59:4642-50
Spielman, J; Lee, R K; Podack, E R (1998) Perforin/Fas-ligand double deficiency is associated with macrophage expansion and severe pancreatitis. J Immunol 161:7063-70
Rukavina, D; Laskarin, G; Rubesa, G et al. (1998) Age-related decline of perforin expression in human cytotoxic T lymphocytes and natural killer cells. Blood 92:2410-20
Baker, M B; Riley, R L; Podack, E R et al. (1997) Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function. Proc Natl Acad Sci U S A 94:1366-71
Nishio, M; Spielman, J; Lee, R K et al. (1996) CD80 (B7.1) and CD54 (intracellular adhesion molecule-1) induce target cell susceptibility to promiscuous cytotoxic T cell lysis. J Immunol 157:4347-53

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