Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA058030-05
Application #
2098746
Study Section
Special Emphasis Panel (SRC (68))
Project Start
1992-08-07
Project End
1997-11-30
Budget Start
1996-06-01
Budget End
1997-11-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Kansas
Department
Pharmacology
Type
Schools of Medicine
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160
Weroha, S John; Li, Sara Antonia; Tawfik, Ossama et al. (2006) Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats. Carcinogenesis 27:491-8
Li, Jonathan J; Li, Sara Antonia (2003) Causation and prevention of solely estrogen-induced oncogenesis: similarities to human ductal breast cancer. Adv Exp Med Biol 532:195-207
Li, S A; Weroha, S J; Tawfik, O et al. (2002) Prevention of solely estrogen-induced mammary tumors in female aci rats by tamoxifen: evidence for estrogen receptor mediation. J Endocrinol 175:297-305
Li, Jonathan J; Papa, Dan; Davis, Marilyn F et al. (2002) Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. Mol Carcinog 33:56-65
Mesia-Vela, Sonia; Sanchez, Rosa I; Li, Jonathan J et al. (2002) Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited. Carcinogenesis 23:1369-72
Li, J J; Weroha, S J; Davis, M F et al. (2001) ER and PR in renomedullary interstitial cells during Syrian hamster estrogen-induced tumorigenesis: evidence for receptor-mediated oncogenesis. Endocrinology 142:4006-14
Liao, D Z; Hou, X; Bai, S et al. (2000) Unusual deregulation of cell cycle components in early and frank estrogen-induced renal neoplasias in the Syrian hamster. Carcinogenesis 21:2167-73
Li, J J; Hou, X; Banerjee, S K et al. (1999) Overexpression and amplification of c-myc in the Syrian hamster kidney during estrogen carcinogenesis: a probable critical role in neoplastic transformation. Cancer Res 59:2340-6
Li, J J; Hou, X; Bentel, J et al. (1998) Prevention of estrogen carcinogenesis in the hamster kidney by ethinylestradiol: some unique properties of a synthetic estrogen. Carcinogenesis 19:471-7
Li, S A; Liao, D Z; Yazlovitskaya, E M et al. (1997) Induction of cathepsin D protein during estrogen carcinogenesis: possible role in estrogen-mediated kidney tubular cell damage. Carcinogenesis 18:1375-80

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