Transforming Properties of Gag-Myc Avian Retroviruses

Linial, Maxine L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA058809-03
• Application #: 2099450
• Study Section: Experimental Virology Study Section (EVR)
• Project Start: 1994-01-01
• Project End: 1997-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Fred Hutchinson Cancer Research Center
• DUNS #: 075524595
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98109

Publications

Law, W; Linial, M L (2001) Transforming ability of Gag-Myc fusion proteins correlates with Gag-Myc protein stability and transcriptional repression. Oncogene 20:1118-27

Tikhonenko, A T; Black, D J; Linial, M L (1996) Viral Myc oncoproteins in infected fibroblasts down-modulate thrombospondin-1, a possible tumor suppressor gene. J Biol Chem 271:30741-7

Tikhonenko, A T; Black, D J; Linial, M L (1995) v-Myc is invariably required to sustain rapid proliferation of infected cells but in stable cell lines becomes dispensable for other traits of the transformed phenotype. Oncogene 11:1499-508