Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA058919-03
Application #
2099535
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1994-05-16
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Xiao, Suhong; Hansen, Deborah K; Horsley, Elizabeth T M et al. (2005) Maternal folate deficiency results in selective upregulation of folate receptors and heterogeneous nuclear ribonucleoprotein-E1 associated with multiple subtle aberrations in fetal tissues. Birth Defects Res A Clin Mol Teratol 73:6-28
Antony, Ayyok; Tang, Ying-Sheng; Khan, Rehana A et al. (2004) Translational upregulation of folate receptors is mediated by homocysteine via RNA-heterogeneous nuclear ribonucleoprotein E1 interactions. J Clin Invest 113:285-301
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Zhang, Yonghua; Guo, Lili; Roeske, Roger W et al. (2004) Pteroyl-gamma-glutamate-cysteine synthesis and its application in folate receptor-mediated cancer cell targeting using folate-tethered liposomes. Anal Biochem 332:168-77
Antony, Ayyok C (2004) Folate receptors: reflections on a personal odyssey and a perspective on unfolding truth. Adv Drug Deliv Rev 56:1059-66
Antony, Ayyok C (2003) Vegetarianism and vitamin B-12 (cobalamin) deficiency. Am J Clin Nutr 78:3-6
Pillai, M R; Chacko, P; Kesari, L A et al. (2003) Expression of folate receptors and heterogeneous nuclear ribonucleoprotein E1 in women with human papillomavirus mediated transformation of cervical tissue to cancer. J Clin Pathol 56:569-74
Xiao, X; Tang, Y S; Mackins, J Y et al. (2001) Isolation and characterization of a folate receptor mRNA-binding trans-factor from human placenta. Evidence favoring identity with heterogeneous nuclear ribonucleoprotein E1. J Biol Chem 276:41510-7
Antony, A C; Hansen, D K (2000) Hypothesis: folate-responsive neural tube defects and neurocristopathies. Teratology 62:42-50
Sun, X L; Jayaram, H N; Gharehbaghi, K et al. (1999) Modulation of the cytotoxicity of 3'-azido-3'-deoxythymidine and methotrexate after transduction of folate receptor cDNA into human cervical carcinoma: identification of a correlation between folate receptor expression and thymidine kinase activity. Cancer Res 59:940-6

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