Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA059127-04
Application #
2099758
Study Section
Special Emphasis Panel (SRC (64))
Project Start
1993-03-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1997-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Miscellaneous
Type
Schools of Earth Sciences/Natur
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Lundberg, P; Splitter, G A (2000) gammadelta(+) T-Lp6phocyte cytotoxicity against envelope-expressing target cells is unique to the alymphocytic state of bovine leukemia virus infection in the natural host. J Virol 74:8299-306
Pyeon, D; Diaz, F J; Splitter, G A (2000) Prostaglandin E(2) increases bovine leukemia virus tax and pol mRNA levels via cyclooxygenase 2: regulation by interleukin-2, interleukin-10, and bovine leukemia virus. J Virol 74:5740-5
Pyeon, D; Splitter, G A (1999) Regulation of bovine leukemia virus tax and pol mRNA levels by interleukin-2 and -10. J Virol 73:8427-34
Pyeon, D; Splitter, G A (1998) Interleukin-12 p40 mRNA expression in bovine leukemia virus-infected animals: increase in alymphocytosis but decrease in persistent lymphocytosis. J Virol 72:6917-21
Orlik, O; Ban, J; Hlavaty, J et al. (1997) Polyclonal bovine sera but not virus-neutralizing monoclonal antibodies block bovine leukemia virus (BLV) gp51 binding to recombinant BLV receptor BLVRcp1. J Virol 71:3263-7
Splitter, G (1997) Cytokines: communication molecules that influence the process of disease. Jpn J Vet Res 45:3-12
Orlik, O; Altaner, C; Splitter, G A (1997) Temperature-dependent non-specific adsorption of recombinant bovine leukemia virus receptor BLVRcp1 in immunoassay. J Immunoassay 18:185-98
Orlik, O; Splitter, G A (1996) Optimization of lymphocyte proliferation assay for cells with high spontaneous proliferation in vitro: CD4+ T cell proliferation in bovine leukemia virus infected animals with persistent lymphocytosis. J Immunol Methods 199:159-65
Orlik, O; Splitter, G A (1996) Progression to persistent lymphocytosis and tumor development in bovine leukemia virus (BLV)-infected cattle correlates with impaired proliferation of CD4+ T cells in response to gag- and env-encoded BLV proteins. J Virol 70:7584-93
Pyeon, D; O'Reilly, K L; Splitter, G A (1996) Increased interleukin-10 mRNA expression in tumor-bearing or persistently lymphocytotic animals infected with bovine leukemia virus. J Virol 70:5706-10

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