Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA059967-02S1
Application #
2100573
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1993-06-18
Project End
1997-03-31
Budget Start
1994-06-01
Budget End
1995-03-31
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Organized Research Units
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Bednarek, A K; Chu, Y; Aldaz, C M (1998) Constitutive telomerase activity in cells with tissue-renewing potential from estrogen-regulated rat tissues. Oncogene 16:381-5
McKenzie, K E; Armstrong, B A; Chen, Y et al. (1997) Alterations in the Ha-ras-1 and the p53 pathway genes in the progression of N-methyl-N-nitrosourea-induced rat mammary tumors. Mol Carcinog 20:194-203
Brenner, A J; Aldaz, C M (1997) The genetics of sporadic breast cancer. Prog Clin Biol Res 396:63-82
Chen, Y; McKenzie, K E; Aldaz, C M et al. (1996) Midkine in the progression of rat N-nitroso-N-methylurea-induced mammary tumors. Mol Carcinog 17:112-6
Chen, K S; Paladugu, A; Aldaz, C M et al. (1996) Cloning and chromosomal localization of the rat Stat5 and Yy1 genes. Cytogenet Cell Genet 74:277-80
Aldaz, C M; Liao, Q Y; Paladugu, A et al. (1996) Allelotypic and cytogenetic characterization of chemically induced mouse mammary tumors: high frequency of chromosome 4 loss of heterozygosity at advanced stages of progression. Mol Carcinog 17:126-33
Aldaz, C M; Liao, Q Y; LaBate, M et al. (1996) Medroxyprogesterone acetate accelerates the development and increases the incidence of mouse mammary tumors induced by dimethylbenzanthracene. Carcinogenesis 17:2069-72
Brenner, A J; Aldaz, C M (1995) Chromosome 9p allelic loss and p16/CDKN2 in breast cancer and evidence of p16 inactivation in immortal breast epithelial cells. Cancer Res 55:2892-5
Aldaz, C M; Chen, T; Sahin, A et al. (1995) Comparative allelotype of in situ and invasive human breast cancer: high frequency of microsatellite instability in lobular breast carcinomas. Cancer Res 55:3976-81
Donehower, L A; Godley, L A; Aldaz, C M et al. (1995) Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes Dev 9:882-95

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