Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060046-03
Application #
2100653
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1994-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Chavali, Gayatri B; Papageorgiou, Anastassios C; Olson, Karen A et al. (2003) The crystal structure of human angiogenin in complex with an antitumor neutralizing antibody. Structure 11:875-85
Olson, Karen A; Byers, H Randolph; Key, Marc E et al. (2002) Inhibition of prostate carcinoma establishment and metastatic growth in mice by an antiangiogenin monoclonal antibody. Int J Cancer 98:923-9
Olson, K A; Byers, H R; Key, M E et al. (2001) Prevention of human prostate tumor metastasis in athymic mice by antisense targeting of human angiogenin. Clin Cancer Res 7:3598-605
Piccoli, R; Olson, K A; Vallee, B L et al. (1998) Chimeric anti-angiogenin antibody cAb 26-2F inhibits the formation of human breast cancer xenografts in athymic mice. Proc Natl Acad Sci U S A 95:4579-83